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IN VITRO FERTILIZATION (FIV)
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IN VITRO FERTILIZATION
In vitro fertilization involves fertilizing an oocyte with a spermatozoon “in vitro”.
That is to say, outside the woman's body, and then implant the fertilized egg in the uterus.
THE IVF WHAT IS IT?
This technique involves several stages that can take an average of 15 days.
During IVF, the egg and sperm are fertilized together in the laboratory.
Embryologists then use high-tech incubators to develop the embryos prior to transfer.
IN WHICH CASES IS IVF INDICATED? ?
VIF can be proposed by your doctor in the following cases:
- When a man's sperm is of poor quality
- When the woman has an abnormality that prevents the sperm and oocyte from meeting (such as an abnormality in the fallopian tubes or endometriosis).
- In case of failureand that the aim is to short-circuit the cervical mucus and facilitate the meeting of spermatozoa with oocytes (female gametes).)in unexplained infertilitye
- In other situations, such as prolonged infertility, advanced age or reduced ovarian reserve.
THE DIFFERENT STAGES OF FIV
Treatment involves a number of stages, calling on the services of different specialists.
To help prepare the uterine lining for implantation, your doctor may also may also prescribe progesterone if a transfer is planned.
- There are many different stimulation protocols, depending on the type of products used and their timing.
They are adapted to each patient, and in the event of failure, the protocol may need to be changed.
VIF: from oocyte to embryo
Day 0: On the day of the puncture, a sample of the partner's sperm is collected, usually by masturbation. usually by masturbation.
It is also possible to thaw a previously frozen sperm sample (sperm flakes).
In all cases, the sample is analyzed and processed in the laboratory.
To select the most mobile spermatozoa.
After puncture, oocytes and sperm are brought into contact and cultured in an incubator for 24 hours. :
- Fertilization then takes place.
JDay 1: the oocytes are examined to see if they have been fertilized.
Day 2: he embryos begin to divide, growing from 2 to 4 cells.
Day 3: embryonic division accelerates, from 4 to 8 cells.
Vers days 5 and 6: the embryos take on a particular shape with a a cavity in the middle and an embryonic button on the side.
This is the blastocyst stage (a blastocyst is a 5/6-day-old embryo with a complex cellular structure composed of about 200 cells).
WHAT SUCCESS RATE FOR IVF ?
It can take more than one IVF cycle to successfully conceive a child. Your fertility doctor may need to adjust your treatment with each attempt.
According to the Agence de la Biomédecine's medical and scientific report, 19.5% of intraconjugal IVF cycles excluding ICSI led to childbirth in 2018. For IVF with ICSI, the rate is 20.1% .
Don't be discouraged if a first cycle doesn't result in pregnancy.
As a reminder, under the most optimal conditions, a 25-year-old woman has a 25% chance of becoming pregnant naturally each cycle.
So failure does not presume your chances of having a baby. Another IVF cycle may be successful.
Unfortunately, there is no guarantee that the treatment will be successful.
VERY IMPORTANT! It's the medical team at our partner clinics who will decide which medical procedures are best suited to each patient's situation! You are the only one, together with the doctors, to decide on the desired care.
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